G030
GMP Recombinant Human IL-1A
Size
£661.00
- SKU:
- G030
- Additional Names:
- IL-1 alpha, IL1A, IL-1 ALPHA, IL1F1, IL-1α
- Application:
- Functional Assay
- Molecular Weight:
- 18.0 kDa
- Purity:
- ≥95% by SDS-PAGE
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Host:
- E. coli
- ABP:
- No Import Docs
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
- Format:
- Lyophilized powder
- Extra Details:
- IL-1α (Interleukin-1α), a key member of the interleukin-1 (IL-1) family, shares a similar β-trefoil topology with other IL-1 family members such as IL-1β, despite low sequence homology. Like IL-1β, it exerts its biological functions by binding to the interleukin-1 receptor (IL-1R). IL-1α is a pleiotropic cytokine that plays a central role in inflammation, immune responses, and cell proliferation.In in vitro cell culture, IL-1α stimulates monocytes/macrophages and dendritic cells to secrete other cytokines, thereby mimicking an inflammatory environment. It also promotes the proliferation of fibroblasts and endothelial cells, making it a useful tool in wound healing and angiogenesis research.
- Shipping Conditions:
- Blue Ice