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G029

GMP Recombinant Human M-CSF

Size

£651.00

SKU:
G029
Additional Names:
Macrophage Colony-Stimulating Factor, CSF1
Application:
Functional Assay
Molecular Weight:
18.4 kDa
Purity:
≥95% by SDS-PAGE
Storage Conditions:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Supplier:
East-Mab Biomedical
Host:
E. coli
ABP:
No Import Docs
Formulation:
Lyophilized from a 0.22 um filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
Format:
Lyophilized powder
Extra Details:
M-CSF (Macrophage Colony-Stimulating Factor) is an important glycoprotein cytokine that exists as a disulfide-linked homodimer. It plays a key role in regulating the proliferation, differentiation, and survival of the monocyte-macrophage lineage. M-CSF promotes the proliferation of monocytes/macrophages, supports the differentiation of hematopoietic stem cells into monocytes and their subsequent development into macrophages, and enhances macrophage survival through anti-apoptotic signaling (e.g., upregulation of Bcl-2). Additionally, it modulates functional polarization and influences macrophage phenotype.
Shipping Conditions:
Blue Ice