G005
GMP Recombinant Human IL-21
Size
£755.00
- SKU:
- G005
- Additional Names:
- IL21, Za11, Interleukin-21
- Application:
- Functional Assay
- Molecular Weight:
- 15.9 kDa
- Purity:
- ≥95% by SDS-PAGE
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Host:
- Hamster
- ABP:
- No Import Docs
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH 7.4
- Format:
- Lyophilized powder
- Extra Details:
- IL-21 (Interleukin-21) is a pleiotropic cytokine belonging to the common gamma-chain (γc) cytokine family, primarily produced by activated CD4+ T cells and natural killer T (NKT) cells. It plays important roles in immune regulation, cell proliferation, differentiation, and functional modulation. In B cell cultures, IL-21 induces plasma cell differentiation and enhances the secretion of IgG and IgM. In T cells, it promotes the proliferation and cytotoxicity of CD8+ T cells and NK cells, making it valuable for tumor immunotherapy research, such as in CAR-T cell cultivation. Additionally, IL-21 can suppress regulatory T cell (Treg) function and enhance the anti-tumor activity of effector T cells. In NK cell cultures, it augments killing capacity and IFN-γ secretion, and is widely used in studies related to immune cell therapy.
- Shipping Conditions:
- Blue Ice