G004
GMP Recombinant Human IL-7
Size
£810.00
- SKU:
- G004
- Additional Names:
- IL7, Interleukin-7
- Application:
- Functional Assay
- Molecular Weight:
- 17.3 kDa
- Purity:
- ≥95% by SDS-PAGE
- Storage Conditions:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Supplier:
- East-Mab Biomedical
- Host:
- Hamster
- ABP:
- No Import Docs
- Formulation:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH7.4
- Format:
- Lyophilized powder
- Extra Details:
- IL-7 (Interleukin-7) is a cytokine produced by bone marrow stromal cells, thymic epithelial cells, and other cell types. It belongs to the four-helix bundle cytokine family and exerts its functions primarily by binding to the IL-7 receptor, thereby activating signaling pathways such as JAK-STAT, PI3K-AKT, and MAPK. IL-7 plays an essential role in the immune system, particularly in T cell development, survival, and homeostatic proliferation. In?in vitro?cultures, IL-7 supports the survival of na?ve and memory T cells and helps prevent apoptosis. During early B cell development, it promotes both proliferation and differentiation. In the context of cell therapy—such as CAR-T or TCR-T treatments—IL-7 is often used in combination with other cytokines like IL-15 to enhance T cell expansion and maintain stem-like properties. Furthermore, IL-7 can improve the yield and activity of tumor-infiltrating lymphocytes (TILs) or virus-specific T cells during culture.
- Shipping Conditions:
- Blue Ice