TAU
Anti-Tau Antibody
Size
£563.00
- SKU:
- TAU
- Additional Names:
- Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau
- Application:
- IHC, ICC
- Concentration:
- 200 ug/ml
- Physical State:
- Liquid
- Molecular Weight:
- 55-62 kDa
- Species Reactivity:
- Human, Mouse, Rat
- Purification:
- Chickens were immunized with two synthetic peptide / keyhole limpet hemocyanin (KLH) conjugates. These synthetic peptides corresponded to different and nonphosphorylated regions of the Tau gene product, but are shared between the human (NP_05819, NCBI) and mouse (P01637, NCBI) sequences. After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity purified using a peptide column, and the concentrations of the eluates adjusted to 200 ug/mL. Finally, equal volumes of both of these affinity-purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized.
- Storage Conditions:
- 2-8[o]C Protect from light.
- Supplier:
- Aves Labs
- Host:
- Chicken/Avian
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline ("PBS,"
- Immunogen:
- Synthetic peptides
- Formulation:
- Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline ("PBS," pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.
- Format:
- Affinity-Purified IgY
- Uniprot:
- P10636
- Synonyms:
- DDPAC;FTDP-17;G protein beta1/gamma2 subunit-interacting factor 1;MAPTL;microtubule-associated protein tau;MSTD;MTBT1;MTBT2;neurofibrillary tangle protein;paired helical filament-tau;PHF-tau;PPND;PPP1R103;protein phosphatase 1, regulatory subunit 103;TAU;tau-40
- Extra Details:
- Antipeptide antibodies were generated in chickens against two sequences shared between the mouse (P10637.3) and human (P10636.5) gene products. Neither of these sequences contain phosphorylated serine or threonine residues, so these Tau antibodies recognize both the euphosphorylated and hyperphosphorylated forms of Tau. Antibodies were affinity-purified from IgY fractions prepared from yolks collected from hyperimmunized hens. These antibodies have been validated with human, mouse and rat tissues., Aves Labs
- Shipping Conditions:
- Blue Ice