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  2. Polyclonal

ER2-3

Anti-Metabotropic Glutamate Receptor Type 2/Type 3 (mGluR2/mGluR3) Antibody

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£563.00

SKU:
ER2-3
Additional Names:
Metabotropic glutamate receptor 2, mGluR2, Metabotropic glutamate receptor 3, mGluR3
Application:
IHC, ICC
Concentration:
200 ug/ml
Physical State:
Liquid
Molecular Weight:
99 kDa
Species Reactivity:
Human, Mouse, Rat
Purification:
Chickens were immunized with two synthetic peptide / keyhole limpet hemocyanin (KLH) conjugates. These synthetic peptides corresponded to unique sequences within the metabotropic glutamate receptor type 2 and type 3 gene products, but was shared between the human (Q14416.2, Q14832.2 NCBI) and mouse (Q14B12.2, Q9QYS2.1, NCBI) sequences. After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity purified using a peptide column, the concentrations of the eluates adjusted to 200 ug/mL, and the preparation was filter-sterilized.
Storage Conditions:
2-8[o]C Protect from light.
Supplier:
Aves Labs
Host:
Chicken/Avian
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline ("PBS,"
Immunogen:
Synthetic peptides
Formulation:
Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline ("PBS," pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.
Format:
Affinity-Purified IgY
Uniprot:
Q14416
Synonyms:
GLUR2;glutamate receptor homolog;glutamate receptor, metabotropic 2;GPRC1B;metabotropic glutamate receptor 2;mGlu2;MGLUR2
Extra Details:
We have three different anti-mGluR antibodies, each of which binds to a specific peptide sequence(s) present in different sets of mGluR gene family members. The ER2/3 antibody represents sequences found in both mGluR2 and mGluR3. (Note that this product cannot distinguish between these two receptors.) It comprises two antipeptide antibodies generated against overlapping sequences specific to the mGluR2 and mGluR3 gene products but not found in other mGluR gene family members. This antibody has been validated for immunohistochemistry and immunocytochemistry using mouse brain sections and cultured neuroblastoma cells as well as in rat brain sections., Aves Labs
Shipping Conditions:
Blue Ice