AID00601
Recombinant Human PLA2R1 Protein
Size
£168.00
- SKU:
- AID00601
- Additional Names:
- PLA2R,180kDasecretoryphospholipaseA2receptor,SecretoryphospholipaseA2receptor,PLA2-R,M-typereceptor,C-typelectindomainfamily13memberC,SolublePLA2-R,PLA2R1,SolublePLA2R,CLEC13C
- Physical State:
- Lyophilized
- Purity:
- >95% as determined by sds-page.
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- AntibodySystems
- Buffer:
- LyophilizedfromasolutioninPBSpH7.4,0.02%NLS,1mMEDTA,4%Trehalose,1%Mannitol.
- Species:
- Human
- Uniprot:
- Q13018
- Synonyms:
- 180 kDa secretory phospholipase A2 receptor;C-type lectin domain family 13 member C;CLEC13C;M-type receptor;phospholipase A2 receptor 1, 180kD;phospholipase A2 receptor 1, 180kDa;PLA2-R;PLA2G1R;PLA2IR;PLA2R;secretory phospholipase A2 receptor
- Extra Details:
- PLA2R1isalargetransmembranereceptorof180-kDathatbelongstothesuperfamilyofC-typelectins.ItwasdiscoveredbecauseofitshighaffinityforsecretedphospholipasesA2(sPLA2),enzymesthatplayakeyroleinlipidmediatorsynthesis.EarlyPLA2R1physiologicalrolesincludetheclearanceofsPLA2fromtheextracellularmediumand/orpromotionoftheiractions.Overthelastfouryears,twoindependentstudiessuggestedthatPLA2R1playsaroleincancerasatumorgenesuppressorandisthemajortargetantigenofauto-immuneantibodiesinvolvedinidiopathicmembranousnephropathy,aseverehumankidneydisease.
- Shipping Conditions:
- Dry Ice