AID00101
Recombinant Human CADM-140/MDA5 Protein
Size
£232.00
- SKU:
- AID00101
- Additional Names:
- MDA-5,IFIH1,Helicard,Clinicallyamyopathicdermatomyositisautoantigen140kDa,Interferon-inducedwithhelicaseCdomainprotein1,Helicasewith2CARDdomains,RNAhelicase-DEADboxprotein116,RIG-I-likereceptor2,Interferon-inducedhelicaseCdomain-containingprotein1,MDA5,Murabutidedown-regulatedprotein,Melanomadifferentiation-associatedprotein5,CADM-140autoantigen,RH116,RLR-2
- Physical State:
- Liquid
- Purity:
- >95% as determined by sds-page.
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Supplier:
- AntibodySystems
- Buffer:
- 20mMTris-HCl,pH8.0,100mMNaCl,1mMDTT,10%Glycerol.
- Species:
- Human
- Uniprot:
- Q9BYX4
- Synonyms:
- AGS7;CADM-140 autoantigen;clinically amyopathic dermatomyositis autoantigen 140 kDa;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide;helicard;helicase with 2 CARD domains;Hlcd;IDDM19;interferon-induced helicase C domain-containing protein 1;Interferon-induced with helicase C domain protein 1;MDA-5;MDA5;melanoma differentiation-associated gene 5;melanoma differentiation-associated protein 5;murabutide down-regulated protein;RIG-I-like receptor 2;RLR-2;RNA helicase-DEAD box protein 116;SGMRT1
- Extra Details:
- MDA5/IFIH1istheCADM-140autoantigen,involvedinclinicallyamyopathicdermatomyositis(CADM).Thisisachronicinflammatorydisorderthatshowstypicalskinmanifestationsofdermatomyositisbuthasnoorlittleevidenceofclinicalmyositis.Anti-CADM-140antibodiesappeartobespecifictodermatomyositis,especiallyCADM.Patientswithanti-CADM-140antibodiesfrequentlydeveloplife-threateningacuteprogressiveinterstitiallungdisease(ILD).
- Shipping Conditions:
- Dry Ice