Human ZNRF3 protein, His Tag (MALS & BLI verified)

Cannot supply to this region.

SKU:: ZN3-H52H3
Additional Names:: KIAA1133|RING finger protein 203|RING finger protein 3|RING-type E3 ubiquitin transferase ZNRF3|RNF203|Zinc|ZNRF3
Physical State:: Powder
Molecular Weight:: 19.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: ZNRF3
Species:: Human
Uniprot:: Q9ULT6-1
Synonyms:: RING finger protein 203;RING-type E3 ubiquitin transferase ZNRF3;Zinc/RING finger protein 3
Extra Details:: The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.