Biotinylated Human VSIG3 Protein, Fc,Avitag[TM]

Cannot supply to this region.

SKU:: VS3-H82F9
Additional Names:: Bt-IgSF|CT119|CXADRL1|IgSF11|VSIG3
Physical State:: Powder
Molecular Weight:: 51.5 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: Tris with Glycine, Arginine and NaCl, pH7.5
Immunogen:: VSIG3
Species:: Human
Uniprot:: Q5DX21-1
Synonyms:: Brain and testis-specific immunoglobulin superfamily protein;V-set and immunoglobulin domain-containing protein 3
Extra Details:: VSIG3, also known as IGSF11, BT-IgSF, and CLMP, is a homophilic adhesion molecule that preferentially expressed in the brain. The function of VSIG3 is to stimulate cell growth through homophilic interactions. In clinical, the VSIG3 has been reported to as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. In addition, VSIG-3 is also a ligand of B7 family member VISTA/PD-1H and inhibits human T-cell functions through a novel VSIG-3/VISTA pathway. VSIG-3/VISTA co-inhibitory pathway may provide new strategies for the treatment of human cancers and autoimmune disorders.