Human Truncated Vitronectin / VTN-N Protein, premium grade

Cannot supply to this region.

SKU:: VIN-H5117
Physical State:: Liquid
Molecular Weight:: 47.6 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS, 0.15 M Arginine, 0.5 mM EDTA, 250 mM N-Acetyl-L-cysteine, pH7.4
Immunogen:: Vitronectin
Species:: Human
Uniprot:: P04004
Synonyms:: complement S-protein;epibolin;S-protein;serum spreading factor;Serum-spreading factor;somatomedin B;V75;vitronectin;VN;VNT
Extra Details:: Vitronectin is also known as S-protein, VN, VTN, V75. Vitronectin, a multifunctional glycoprotein, is involved in coagulation, inhibition of the formation of the membrane attack complex (MAC), cell adhesion and migration, wound healing, and tissue remodeling. The primary cellular source of vitronectin is hepatocytes. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.