US1-H5254
Human USAG-1 Protein, Fc Tag
Cannot supply to this region.
- SKU:
- US1-H5254
- Additional Names:
- Uterine sensitization-associated gene 1 protein
- Physical State:
- Powder
- Molecular Weight:
- 47.2 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- USAG-1
- Species:
- Human
- Uniprot:
- Q6X4U4-1
- Synonyms:
- Ectodermal BMP inhibitor;Uterine sensitization-associated gene 1 protein
- Extra Details:
- USAG1 (uterine sensitization associated gene 1), also known asSOSTDC1 (sclerostin domain-containing 1), Ectodin, is a secreted protein with a glycosylated N-terminus that contains a C-terminal cysteine knot domain. This C-terminal cysteine knot domain is present in numerous growth factors, including TGFB Beta, NGF, PDGF, vWF, NDP, and mucin-2, and involved in dimerization, receptor binding, and signal transduction. SOSTDC1 negatively regulates BMP signaling during cellular proliferation, differentiation, and apoptosis in several biological processes (such as dentary morphogenesis, embryo implantation in the endo-metrium, and healing of bone fractures) [8]. In addition, SOSTDC1 might also involve cancer development processes through the regulation of the Wnt pathway.
- Shipping Conditions:
- Ambient