![Biotinylated Human cytomegalovirus (strain AD169) (HHV-5) & Human UL18 & B2M Heterodimer Protein, His,Avitag[TM]&Tag Free (MALS verified)](https://console.acrobiosystems.com/public/product/images/sds/ULM-V82W3.jpg)
![Biotinylated Human cytomegalovirus (strain AD169) (HHV-5) & Human UL18 & B2M Heterodimer Protein, His,Avitag[TM]&Tag Free (MALS verified)](https://console.acrobiosystems.com/public/product/images/spr/ULM-V82W3-S1.jpg)
ULM-V82W3
Biotinylated Human cytomegalovirus (strain AD169) (HHV-5) & Human UL18 & B2M Heterodimer Protein, His,Avitag[TM]&Tag Free (MALS verified)
Cannot supply to this region.
- SKU:
- ULM-V82W3
- Physical State:
- Powder
- Molecular Weight:
- 36.0 kDa (UL18) & 11.7 kDa (B2M)
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- UL18 & B2M
- Species:
- Human, Virus
- Uniprot:
- P08560, P61769
- Synonyms:
- beta chain of MHC class I molecules;beta-2-microglobin;beta-2-microglobulin;IMD43
- Extra Details:
- Human cytomegalovirus (HCMV) encodes UL18, a viral MHC-I homolog that mimics human HLA class I molecules. UL18 forms a stable heterodimer with human B Beta2-microglobulin (B2M), enabling proper folding and high-affinity interaction with the inhibitory receptor LIR-1/ILT2 on immune cells. This interaction suppresses NK-cell activation and contributes to HCMV immune evasion. Recombinant UL18-B2M complexes are widely used to study viral immunomodulation and receptor-ligand interactions.
- Shipping Conditions:
- Ambient