Biotinylated Human TROP-2 / TACSTD2 Protein, Fc,Avitag[TM]

Cannot supply to this region.

SKU:: TR2-H82F4
Physical State:: Powder
Molecular Weight:: 55.6 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Immunogen:: TROP-2
Species:: Human
Uniprot:: P09758-1
Synonyms:: Cell surface glycoprotein Trop-2;Membrane component chromosome 1 surface marker 1;Pancreatic carcinoma marker protein GA733-1
Extra Details:: TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.