TR2-H5258
Human TREM2 (19-157) Protein, Fc Tag
Cannot supply to this region.
- SKU:
- TR2-H5258
- Physical State:
- Powder
- Molecular Weight:
- 42.1 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Immunogen:
- TREM2
- Species:
- Human
- Uniprot:
- Q9NZC2-1
- Synonyms:
- Triggering receptor expressed on monocytes 2
- Extra Details:
- Triggering Receptor Expressed on Myeloid cells 2 (TREM2) is a pivotal cell-surface receptor primarily found on microglia in the brain and macrophages in peripheral tissues. Acting as a lipid and amyloid-beta sensor, it signals through the adapter protein DAP12 to regulate immune responses, cell survival, and phagocytosis. In neurobiology, TREM2 is a major focus because its dysfunction is strongly linked to Alzheimer's disease progression and impaired clearance of neurotoxic plaques.
- Shipping Conditions:
- Ambient