Human TREM-1 / CD354 Protein, Fc Tag, low endotoxin

Cannot supply to this region.

SKU:: TR1-H5251
Physical State:: Powder
Molecular Weight:: 46.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: TREM-1
Species:: Human
Uniprot:: Q9NP99-1
Synonyms:: Triggering receptor expressed on monocytes 1
Extra Details:: Triggering receptor expressed on myeloid cells 1 (TREM1) is also known as CD antigen CD354, and is a type I transmembrane protein with a single Ig-like domain. TREM1 is highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. TREM-1 / CD354 stimulates neutrophil and monocyte-mediated inflammatory responses, and also triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. TREM1 can interacts with TYROBP / DAP12.