Biotinylated Mouse TNF-alpha Protein, His,Avitag[TM], active trimer (MALS verified)

Cannot supply to this region.

SKU:: TNA-M82E9
Additional Names:: cachectin|cachexin|DIF|TNF-alpha|TNFA|TNFSF2|TNFA Alpha
Physical State:: Powder
Molecular Weight:: 20.2 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: TNF-alpha
Species:: Mouse
Uniprot:: P06804
Synonyms:: cachectin;DI;DIF;Tn;TNF-;TNF-a;TNF-alpha;Tnfa;TNFalpha;Tnfs;Tnfsf1a;TNFSF2;Tnlg1f;tumor necrosis factor;tumor necrosis factor ligand 1f;tumor necrosis factor ligand superfamily member 2;tumor necrosis factor-alpha
Extra Details:: Tumor necrosis factor alpha (TNFA Alpha) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFA Alpha is in the regulation of immune cells. TNFA Alpha is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFA Alpha production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFA Alpha is used as an immunostimulant under the INN tasonermin. TNFA Alpha can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.