TNA-H5213
Human TNF-alpha Protein, Research Grade
Cannot supply to this region.
- SKU:
- TNA-H5213
- Physical State:
- Powder
- Molecular Weight:
- 17.4 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- TNF-alpha
- Species:
- Human
- Uniprot:
- P01375-1
- Synonyms:
- Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2
- Extra Details:
- Tumor necrosis factor alpha (TNFA Alpha) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFA Alpha is in the regulation of immune cells. TNFA Alpha is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFA Alpha production has been implicated in a variety of human diseases, including major depression, Alzheimers disease and cancer. Recombinant TNFA Alpha is used as an immunostimulant under the INN tasonermin. TNFA Alpha can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
- Shipping Conditions:
- Ambient