Biotinylated Rat Thrombopoietin R Protein, His,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: THR-R82E4
Physical State:: Powder
Molecular Weight:: 57.4 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Thrombopoietin R
Species:: Rat
Uniprot:: A0A1W2Q6N1
Synonyms:: Myeloproliferative leukemia protein;Proto-oncogene c-Mpl
Extra Details:: Thrombopoietin R, also known as TPO-R, is expressed predominantly on the surface of MKs, platelets, hemangioblasts, and hematopoietic stem cells (HSCs). Binding of TPO to the megakaryocyte TPO-R leads to different effects: prevention of megakaryocyte apoptosis; increased megakaryocyte number, size, and ploidy; increasing rate of megakaryocyte maturation; and internalization of the TPO/TPO-R complex. Thrombopoietin R involved in multiple signal transduction pathways, such as JAK, STAT, and MAP kinase.