Mouse Thrombopoietin R Protein, His Tag, low endotoxin

Cannot supply to this region.

SKU:: THR-M52H4
Physical State:: Powder
Molecular Weight:: 54 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Thrombopoietin R
Species:: Mouse
Uniprot:: A2A9D4
Synonyms:: Myeloproliferative leukemia protein;Proto-oncogene c-Mpl
Extra Details:: Thrombopoietin R, also known as TPO-R, is expressed predominantly on the surface of MKs, platelets, hemangioblasts, and hematopoietic stem cells (HSCs). Binding of TPO to the megakaryocyte TPO-R leads to different effects: prevention of megakaryocyte apoptosis; increased megakaryocyte number, size, and ploidy; increasing rate of megakaryocyte maturation; and internalization of the TPO/TPO-R complex. Thrombopoietin R involved in multiple signal transduction pathways, such as JAK, STAT, and MAP kinase.