THR-H52H7
Human Thrombopoietin R / TPO R Protein, His Tag, low endotoxin (MALS & SPR verified)
Cannot supply to this region.
- SKU:
- THR-H52H7
- Additional Names:
- C-MPL|CD110|MPL|MPLV|THCYT2|TPOR
- Physical State:
- Powder
- Molecular Weight:
- 54.4 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- Thrombopoietin R
- Species:
- Human
- Uniprot:
- P40238-1
- Synonyms:
- Myeloproliferative leukemia protein;Proto-oncogene c-Mpl
- Extra Details:
- Thrombopoietin R, also known as TPO-R, is expressed predominantly on the surface of MKs, platelets, hemangioblasts, and hematopoietic stem cells (HSCs). Binding of TPO to the megakaryocyte TPO-R leads to different effects: prevention of megakaryocyte apoptosis; increased megakaryocyte number, size, and ploidy; increasing rate of megakaryocyte maturation; and internalization of the TPO/TPO-R complex. Thrombopoietin R involved in multiple signal transduction pathways, such as JAK, STAT, and MAP kinase.
- Shipping Conditions:
- Ambient