Cynomolgus Thrombopoietin R / TPO R Protein, His Tag (MALS & SPR verified)

Cannot supply to this region.

SKU:: THR-C52H3
Physical State:: Powder
Molecular Weight:: 54.3 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Thrombopoietin R
Species:: Non-human Primate
Uniprot:: A0A2K5UGC7
Extra Details:: Thrombopoietin R, also known as TPO-R, is expressed predominantly on the surface of MKs, platelets, hemangioblasts, and hematopoietic stem cells (HSCs). Binding of TPO to the megakaryocyte TPO-R leads to different effects: prevention of megakaryocyte apoptosis; increased megakaryocyte number, size, and ploidy; increasing rate of megakaryocyte maturation; and internalization of the TPO/TPO-R complex. Thrombopoietin R involved in multiple signal transduction pathways, such as JAK, STAT, and MAP kinase.