THN-H5217
Human Thrombopoietin / TPO Protein, Research Grade
Cannot supply to this region.
- SKU:
- THN-H5217
- Physical State:
- Powder
- Molecular Weight:
- 35.5 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 20 mM NaAc-HAc, pH5.0
- Immunogen:
- Thrombopoietin
- Species:
- Human
- Uniprot:
- P40225-1
- Synonyms:
- C-mpl ligand;Megakaryocyte colony-stimulating factor;Megakaryocyte growth and development factor;Myeloproliferative leukemia virus oncogene ligand
- Extra Details:
- Thrombopoietin (TPO) is a 332 amino acid glycoprotein made primarily in the liver and act as the major physiological regulator of platelet production. TPO binds the TPO receptor, activates JAK and STAT pathways, thus stimulating megakaryocyte growth and platelet production. Additionally, further investigation uncovered that thrombopoietin is a critical cytokine promoting hematopoietic rebound after myeloablation and its transcripts are expressed by multiple cellular sources.
- Shipping Conditions:
- Ambient