Biotinylated Human Tau-441 / 2N4R (1-441) Protein, His,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: TAU-H81E3
Physical State:: Liquid
Molecular Weight:: 49.5 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 150 mM NaCl, pH7.5
Immunogen:: Tau
Species:: Human
Uniprot:: P10636-8
Synonyms:: Neurofibrillary tangle protein;Paired helical filament-tau
Extra Details:: Tau 441 (2N4R) is the longest human brain tau isoform, containing two N-terminal inserts and four microtubule-binding repeats. It stabilizes neuronal microtubules, but its pathological hyperphosphorylation leads to paired helical filament aggregation. Tau 441 constitutes the core component of neurofibrillary tangles in Alzheimer's disease and related tauopathies.