TAU-H51H3
Human Tau-441 / 2N4R Protein, His Tag, low endotoxin
Cannot supply to this region.
- SKU:
- TAU-H51H3
- Additional Names:
- DDPAC|FTDP-17|MAPT|MSTD|MTBT1|PHF-tau|Tau
- Physical State:
- Powder
- Molecular Weight:
- 47.9 kda
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 150 mM NaCl, pH7.5
- Immunogen:
- Tau
- Species:
- Human
- Uniprot:
- P10636-8
- Synonyms:
- Neurofibrillary tangle protein;Paired helical filament-tau
- Extra Details:
- Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies. Tau-441 is known as "2N4R," "Isoform Tau-F," "Tau-4" or "Tau 441", which consisting of 441 amino acid. Tau-441 is a potential therapeutic target for pathogenesis.
- Shipping Conditions:
- Ambient