TA2-H55D3
Human TAP1 & TAP2 Full Length Protein, Flag,His Tag&Flag,Twin-Strep Tag (Detergent)
Cannot supply to this region.
- SKU:
- TA2-H55D3
- Physical State:
- Liquid
- Molecular Weight:
- 84.9 kDa & 81.1 kDa
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM HEPES, 150 mM NaCl, DDM, pH7.5, CHS
- Immunogen:
- TAP1 & TAP2
- Species:
- Human
- Uniprot:
- Q03518-1, Q03519-1
- Synonyms:
- ATP-binding cassette sub-family B member 2;ATP-binding cassette sub-family B member 3;Peptide supply factor 1;Peptide supply factor 2;Peptide transporter involved in antigen processing 1;Peptide transporter involved in antigen processing 2;Peptide transporter PSF1;Peptide transporter PSF2;Peptide transporter TAP1;Peptide transporter TAP2;Really interesting new gene 11 protein;Really interesting new gene 4 protein
- Extra Details:
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Dry Ice