SARS S protein (R667A, K968P, V969P), His Tag (MALS verified)

Cannot supply to this region.

SKU:: SPN-S52H6
Additional Names:: S glycoprotein|S protein|Spike|Spike glycoprotein
Physical State:: Powder
Molecular Weight:: 136.3 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 150 mM NaCl, 0.2 M Sodium citrate, pH5.5
Immunogen:: Spike protein
Species:: Virus
Extra Details:: SARS S protein (R667A, K968P, V969P), His Tag (SPN-S52H6) is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # AAP13567.1 (R667A, K968P, V969P)). The recombinant protein is expressed with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (K968P, V969P) and alanine substitutions (R667A) are introduced to stabilize the trimeric prefusion state of SARS-CoV S protein and abolish the furin cleavage site, respectively.