Biotinylated Mouse SOST / Sclerostin Protein, Avitag[TM],His Tag (HPLC verified)

Cannot supply to this region.

SKU:: SOT-M82E3
Physical State:: Powder
Molecular Weight:: 24.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS, 0.2 M Arginine, pH7.4
Immunogen:: SOST
Species:: Mouse
Uniprot:: Q99P68
Synonyms:: 5430411E23Rik;sclerostin
Extra Details:: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008]