Human SOD1 / Cu-Zn SOD Protein, His Tag, low Endotoxin (active enzyme)

Cannot supply to this region.

SKU:: SO1-H5148
Additional Names:: hSod1|SOD1|Superoxide dismutase 1
Physical State:: Powder
Molecular Weight:: 16.8 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM Tris, 150 mM NaCl, pH7.5
Immunogen:: SOD1
Species:: Human
Uniprot:: P00441
Synonyms:: ALS;ALS1;Cu/Zn superoxide dismutase;epididymis secretory protein Li 44;HEL-S-44;homodimer;hSod1;indophenoloxidase A;IPOA;SOD;SOD, soluble;STAHP;superoxide dismutase [Cu-Zn];Superoxide dismutase 1;superoxide dismutase 1, soluble;superoxide dismutase, cystolic
Extra Details:: Superoxide dismutase [Cu-Zn] (SOD1) is also known as superoxide dismutase 1 (hSod1), an enzyme that in humans is encoded by the SOD1 gene, located on chromosome 21. SOD1 can bind copper and zinc ions and is one of three superoxide dismutases responsible for destroying free superoxide radicals in the body. The encoded isozyme (SOD1) is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide. Furthermore, the mutations of SOD1 gene can result in a neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord.