SIR-H5255
Human SIGIRR Protein, Fc Tag (MALS verified)
Cannot supply to this region.
- SKU:
- SIR-H5255
- Additional Names:
- interleukin-1 receptor 8|Single Ig IL-1-related receptor|Single Ig IL-1R-related molecule|Single immunoglobulin domain-containing IL1R-related protein|TIR8|Toll
- Physical State:
- Powder
- Molecular Weight:
- 39.0 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- SIGIRR
- Species:
- Human
- Uniprot:
- Q6IA17-1
- Synonyms:
- Single Ig IL-1R-related molecule;Single immunoglobulin domain-containing IL1R-related protein;Toll/interleukin-1 receptor 8
- Extra Details:
- Single immunoglobulin IL-1-related receptor (SIGIRR), which is also known as Toll/interleukin-1 receptor 8, is a member of the interleukin-1 receptor (IL-1R) family. SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
- Shipping Conditions:
- Ambient