Human SIRP beta / CD172b Protein, Fc Tag (MALS verified)

Cannot supply to this region.

SKU:: SIA-H5257
Additional Names:: 9930027N05Rik|CD172b|CD172b antigen|DKFZp686A05192|FLJ26614|SIRP beta 1|SIRP-beta|SIRP-BETA-1|SIRPB1
Physical State:: Powder
Molecular Weight:: 63.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: Tris with Glycine, Arginine and NaCl, pH7.5
Immunogen:: SIRP beta
Species:: Human
Uniprot:: O00241-1
Synonyms:: CD172 antigen-like family member B
Extra Details:: Signal-regulatory protein beta-1 (SIRP beta 1) also known as SIRPB Beta1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily. SIRPB Beta1 is a transmembrane protein that has three Ig-like domains in its extracellular region and a short cytoplasmic tail. Human SIRPB Beta1 is expressed on monocytes and granulocytes but not on lymphocytes. SIRP beta 1 contains short cytoplasmic domains that lack cytoplasmic sequence motifs capable of recruiting SHP-2 and SHP-1. In addition, they contain a single basic lysine residue within the hydrophobic transmembrane domain.