SI0-H52H9
Human Siglec-10 Protein, His Tag (MALS verified)
Cannot supply to this region.
- SKU:
- SI0-H52H9
- Additional Names:
- MGC126774|PRO940|SIGLEC10|SLG2
- Physical State:
- Powder
- Molecular Weight:
- 60.1 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 25 mM MES, 150 mM NaCl, Arginine, pH5.5
- Immunogen:
- Siglec-10
- Species:
- Human
- Uniprot:
- Q96LC7-1
- Synonyms:
- Siglec-like protein 2
- Extra Details:
- The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
- Shipping Conditions:
- Ambient