Human Siglec-15 / CD33L3 Protein, Fc Tag

Cannot supply to this region.

SKU:: SG5-H5253
Additional Names:: CD33 antigen-like 3|CD33L3|sialic acid-binding Ig-like lectin 15|SIGLEC-15|Siglec15
Physical State:: Powder
Molecular Weight:: 53.0 kda
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Siglec-15
Species:: Human
Uniprot:: Q6ZMC9-1
Synonyms:: CD33 antigen-like 3
Extra Details:: Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.