SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag

Cannot supply to this region.

SKU:: S2N-C52HE
Additional Names:: S glycoprotein Subunit2|S2 protein|Spike|Spike glycoprotein Subunit2|Spike protein S2
Physical State:: Powder
Molecular Weight:: 59.9 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Spike S2
Species:: Virus
Extra Details:: SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag (S2N-C52He) is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P/ A892P/ A899P/ A942P/ K986P/ V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein. The T1027I/ V1176F mutations were identified identified in the SARS-CoV-2 Gamma variant (Pango lineage: P.1; other names: 20J/501Y.V3).