Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric monoclonal antibody, Human IgG1 (AM122)

Cannot supply to this region.

SKU:: S1N-M122
Physical State:: Powder
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Reactivities:: Mouse
Buffer:: PBS (pH 7.4)
Immunogen:: Spike RBD
Clone:: AM122
Extra Details:: Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) is a chimeric monoclonal antibody recombinantly expressed in HEK293 cells, which combines the variable regions of a mouse monoclonal antibody with human IgG1 constant domains. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2) and Omicron (B.1.1.529).