RS1-H4221
Human R-Spondin 1 / RSPO1 Protein, His Tag
Cannot supply to this region.
- SKU:
- RS1-H4221
- Additional Names:
- CRISTIN3|FLJ40906|R-spondin-1|RP11-566C13.1|RSPO1
- Physical State:
- Powder
- Molecular Weight:
- 28.7 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- R-Spondin 1
- Species:
- Human
- Uniprot:
- Q2MKA7-1
- Synonyms:
- Roof plate-specific spondin-1
- Extra Details:
- R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/B Beta-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for B Beta-catenin stabilization. A putative nuclear localization signal at the C-terminus may allow some expression in the nucleus.
- Shipping Conditions:
- Ambient