Biotinylated Mouse PSMA / FOLH1 Protein, His,Avitag[TM]

Cannot supply to this region.

SKU:: PSA-M82Q4
Physical State:: Liquid
Molecular Weight:: 83.2 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 25 mM MES, 500 mM NaCl, pH6.5
Immunogen:: PSMA
Species:: Mouse
Uniprot:: O35409-1
Synonyms:: Folate hydrolase 1;Folylpoly-gamma-glutamate carboxypeptidase;Glutamate carboxypeptidase II;Membrane glutamate carboxypeptidase;N-acetylated-alpha-linked acidic dipeptidase I;Prostate-specific membrane antigen homolog;Pteroylpoly-gamma-glutamate carboxypeptidase
Extra Details:: Prostate-specific membrane antigen (PSMA) is also known as Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), N-acetylated-alpha-linked acidic dipeptidase I (ALAD1), which belongs to the peptidase M28 family and M28B subfamily. FOLH1 / PSMA is stable at pH greater than 6.5. FOLH1 / PSMA is a type II transmembrane zinc metallopeptidase that is most highly expressed in the nervous system, prostate, kidney, and small intestine. FOLH1 / GCP-2 is homodimer and binds 2 zinc ions per subunit, and required for ALADase activity. The catalytic activity of PSMA involved in releasing of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly - gamma - glutamates. FOLH1 / GCP-2 / PSMA has both folate hydrolase and N - acetylated - alpha - linked - acidic dipeptidase (ALADase) activity and has a preference for tri-alpha-glutamate peptides. GCP-2 / PSMA involved in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

Shipping Conditions:: Dry Ice