PSA-HF244
FITC-Labeled Human PSMA / FOLH1 Protein, His Tag
Cannot supply to this region.
- SKU:
- PSA-HF244
- Additional Names:
- FGCP|FOLH|FOLH1|GCPII|GIG27|NAALAD1|NAALADase I|PSM|PSMA
- Physical State:
- Powder
- Molecular Weight:
- 81.4 kDa
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- ACRO Biosystems
- Buffer:
- 25 mM MES, 500 mM NaCl, pH6.5
- Immunogen:
- PSMA
- Species:
- Human
- Uniprot:
- Q04609-1
- Synonyms:
- Cell growth-inhibiting gene 27 protein;Folate hydrolase 1;Folylpoly-gamma-glutamate carboxypeptidase;Glutamate carboxypeptidase II;Membrane glutamate carboxypeptidase;N-acetylated-alpha-linked acidic dipeptidase I;Prostate-specific membrane antigen;Pteroylpoly-gamma-glutamate carboxypeptidase
- Extra Details:
- Prostate-specific membrane antigen (PSMA) is also known as Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1), which belongs to the peptidase M28 family and M28B subfamily. FOLH1 / PSMA is stable at pH greater than 6.5. FOLH1 / PSMA is a type II transmembrane zinc metallopeptidase that is most highly expressed in the nervous system, prostate, kidney, and small intestine. FOLH1 / GCP-2 is homodimer and binds 2 zinc ions per subunit, and required for NAALADase activity. The catalytic activity of PSMA involved in releasing of an unsubstituted, C-terminal glutamyl residue, typically from Ac-Asp-Glu or folylpoly - gamma - glutamates. FOLH1 / GCP-2 / PSMA has both folate hydrolase and N - acetylated - alpha - linked - acidic dipeptidase (NAALADase) activity and has a preference for tri-alpha-glutamate peptides. GCP-2 / PSMA involved in prostate tumor progression and also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
- Shipping Conditions:
- Ambient