Influenza A virus (strain A/Victoria/3/1975 H3N2) Polymerase acidic Protein, His Tag

Cannot supply to this region.

SKU:: PON-V51H3
Physical State:: Liquid
Molecular Weight:: 26.5 kDa
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS, 0.5 M Arginine, Glycerol, pH7.4
Immunogen:: Polymerase acidic protein
Species:: Virus
Uniprot:: P31343-1
Synonyms:: RNA-directed RNA polymerase subunit P2
Extra Details:: Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.