Human PLAU / uPA Protein, His Tag (activated by trypsin) (active enzyme)

Cannot supply to this region.

SKU:: PLU-H5228
Additional Names:: ATF|BDPLT5|PLAU|QPD|u-PA|UPA|URK|Urokinase
Physical State:: Powder
Molecular Weight:: 15.3 kDa, 17.8 kDa and 29.2 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: 25 mM HEPES, 150 mM NaCl, pH7.5
Immunogen:: PLAU
Species:: Human
Uniprot:: P00749-1
Extra Details:: Urokinase - type plasminogen activator is also known as PLAU and UPA, a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys - Pro - Gly - Arg560 - Val561 - Val - Gly - Gly - Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.uPA and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction).