Human Pleiotrophin / PTN Protein, His Tag, premium grade

Cannot supply to this region.

SKU:: PLN-H5244
Physical State:: Powder
Molecular Weight:: 17.2 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Pleiotrophin
Species:: Human
Uniprot:: P21246
Synonyms:: HARP;HB-GAM;HBBM;HBGF-8;HBGF8;HBNF;HBNF-1;heparin affin regulatory protein;heparin-binding brain mitogen;heparin-binding growth factor 8;heparin-binding growth-associated molecule;heparin-binding neurite outgrowth promoting factor;heparin-binding neurite outgrowth-promoting factor 1;NEGF1;OSF-1;osteoblast-specific factor 1;pleiotrophin;pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
Extra Details:: Pleiotrophin and Midkine are structurally related heparin-binding neurotrophic factors, whose expression is developmentally regulated. The expression pattern of these neurotrophic factors suggests function in neurogenesis, cell migration, secondary organogenetic induction, and mesoderm epithelial interaction. The expression of PTN increases during the process of brain embryogenesis, and reaches maximum levels at time of birth. The physiological roles of PTN and Midkine are largely unknown, but these neurotrophins have been implicated in the pathogenesis of neuroblastomas. Recombinant Human Pleiotrophin is a 15.4 kDa protein containing 136 amino acid residues and five intra-molecular disulfide bonds.