Hamster PLBD2 / PLBL2 Protein, His Tag

Cannot supply to this region.

SKU:: PL2-H51H3
Physical State:: Powder
Molecular Weight:: 63.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: PLBD2
Species:: Hamster
Uniprot:: G3I6T1-1
Extra Details:: PLBL2 (also annotated as PLBD2, phospholipase B-like 2) is a lysosome-localized, functionally semi-orphan member of the phospholipase B family. Its mature, active form depends on ordered post-translational processing-signal-peptide removal, mannose-6-phosphate-mediated lysosomal targeting, and an autocatalytic cleavage step. In biopharmaceutical production, especially from CHO cells, PLBL2 is classified among high-risk host cell proteins (HCPs): it persists through downstream purification owing to its stability and clearance-resistant properties, creating a potential immunogenicity hazard (anti-HCP/anti-drug antibody risk) that mandates sensitive, specific monitoring.