PH0-H5219
Human Hyaluronidase PH-20 / SPAM1 Protein, Tag Free (active enzyme, MALS verified)
Cannot supply to this region.
- SKU:
- PH0-H5219
- Additional Names:
- HYA1|HYAL1|HYAL3|HYAL5|PH-20|SPAG15|SPAM1
- Physical State:
- Powder
- Molecular Weight:
- 52.6 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- 50 mM Tris, 100 mM NaCl, pH7.5
- Immunogen:
- Hyaluronidase PH-20
- Species:
- Human
- Uniprot:
- P38567-1
- Synonyms:
- Hyaluronoglucosaminidase PH-20;Sperm adhesion molecule 1;Sperm surface protein PH-20
- Extra Details:
- Hyaluronidase PH-20 is also known as Sperm adhesion molecule 1 (SPAM1) and Sperm surface protein PH-20, which belongs to the glycosyl hydrolase 56 family, SPAM1 / PH-20 is expressed in testis. SPAM-1 / PH20 random hydrolysis of (1->4)-linkages between N - acetyl - beta - D - glucosamine and D-glucuronate residues in hyaluronate. SPAM-1 / PH20 involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. SPAM1 aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
- Shipping Conditions:
- Ambient