PD2-M5254
Mouse PD-L2 / B7-DC Protein, Fc Tag
Cannot supply to this region.
- SKU:
- PD2-M5254
- Additional Names:
- Butyrophilin B7-DC|CD273|PD-L2|PDCD1 ligand 2|PDCD1L2|PDCD1LG2|PDL2
- Physical State:
- Powder
- Molecular Weight:
- 49.2 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- Tris with Glycine, Arginine and NaCl, pH7.5
- Immunogen:
- PD-L2
- Species:
- Mouse
- Extra Details:
- Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
- Shipping Conditions:
- Ambient