Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: PD2-H82F6
Additional Names:: Butyrophilin B7-DC|CD273|PD-L2|PDCD1 ligand 2|PDCD1L2|PDCD1LG2|PDL2
Physical State:: Powder
Molecular Weight:: 51.0 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: Tris with Glycine, Arginine and NaCl, pH7.5
Immunogen:: PD-L2
Species:: Human
Uniprot:: Q9BQ51-1
Synonyms:: Butyrophilin B7-DC
Extra Details:: Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.