Cynomolgus PADI4 Protein, His Tag (active enzyme, HPLC verified)

Cannot supply to this region.

SKU:: PA4-C5143
Physical State:: Liquid
Molecular Weight:: 76.1 kda
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 500 mM NaCl, pH8.0
Immunogen:: PADI4
Species:: Non-human Primate
Uniprot:: A0A2K5USI5-1
Extra Details:: Protein arginine deiminase, type 4 (PADI4) is a calcium dependent enzyme Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. PADI4 can interact with tumor suppressor p53 and regulate the transcriptional activity of p53. Dysregulation of PADI4 is implicated in a variety of diseases, including rheumatoid arthritis, tumor development, and multiple sclerosis.