Human P2RY8 Superstable Mutant Protein, Flag,His Tag (Detergent)

Cannot supply to this region.

SKU:: P28-H52D4
Physical State:: Liquid
Molecular Weight:: 53.2 kda
Storage Conditions:: -70[o]C
Supplier:: ACRO Biosystems
Buffer:: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Immunogen:: P2RY8
Species:: Human
Uniprot:: Q86VZ1
Synonyms:: G-protein coupled purinergic receptor P2Y8;P2Y purinoceptor 8;P2Y8;purinergic receptor P2Y, G-protein coupled, 8;purinergic receptor P2Y8
Extra Details:: Purinergic Receptor P2Y8 (P2RY8) is a G protein-coupled receptor primarily expressed in lymphoid tissues. It plays a critical role in B cell signaling and germinal center organization by responding to S1P gradients. Mutations or deletions of P2RY8 are strongly associated with B-cell precursor acute lymphoblastic leukemia and the development of lymphomas.