OR8-C52H1
SARS-CoV-2 ORF8 Protein, His Tag (MALS verified)
Cannot supply to this region.
- SKU:
- OR8-C52H1
- Additional Names:
- ORF8
- Physical State:
- Powder
- Molecular Weight:
- 14.3 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- ORF8
- Species:
- Virus
- Uniprot:
- P0DTC8-1
- Synonyms:
- Non-structural protein 8
- Extra Details:
- The viral protein encoded by open reading frame 8 (ORF8) of SARS-CoV-2, which shares the least homology with SARS-CoV among all viral proteins, directly interacts with MHC-I Iota molecules and mediates their down-regulation. In ORF8-expressing cells, MHC-I Iota molecules are selectively targeted for lysosomal degradation via autophagy. Thus, SARS-CoV-2-infected cells are much less sensitive to lysis by cytotoxic T lymphocytes.
- Shipping Conditions:
- Ambient