Biotinylated Human Neuropilin-2 / NRP2 Protein, His,Avitag[TM] (MALS verified)

Cannot supply to this region.

SKU:: NR2-H82E3
Physical State:: Powder
Molecular Weight:: 98.7 kDa
Storage Conditions:: -20[o]C
Supplier:: ACRO Biosystems
Buffer:: PBS
Immunogen:: Neuropilin-2
Species:: Human
Uniprot:: O60462-1
Synonyms:: Vascular endothelial cell growth factor 165 receptor 2
Extra Details:: Neuropilin-1 (Npn-1, previously known as neuropilin) and Neuropilin-2 (previously known as Npn-1-related molecule) are type I transmembrane proteins that bind distinct members of the class III secreted semaphorin subfamily that are implicated in repulsive axon guidance. Neuropilin extracellular domains contain two CUB (complement-binding) domains, two domains with homology to coagulation factors V and VIII, and a MAM (meprin) domain. In the absence of ligands, neuropilins can form homo- and hetero-oligomers via their MAM domains. Expression in developing neurons of the central and peripheral nervous systems is somewhat overlapping but distinct. Npn-1 and Npn-2 are also receptors for VEGF165 on endothelial and tumor cells.