NR2-H52H3
Human Neuropilin-2 / NRP2 Protein, His Tag (MALS verified)
Cannot supply to this region.
- SKU:
- NR2-H52H3
- Additional Names:
- Neuropilin-2|Neuropilin2|NRP2|Vascular endothelial cell growth factor 165 receptor 2|VEGF165R2
- Physical State:
- Powder
- Molecular Weight:
- 97.0 kDa
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Buffer:
- PBS
- Immunogen:
- Neuropilin-2
- Species:
- Human
- Uniprot:
- O60462-1
- Synonyms:
- Vascular endothelial cell growth factor 165 receptor 2
- Extra Details:
- Neuropilin-1 (Npn-1, previously known as neuropilin) and Neuropilin-2 (previously known as Npn-1-related molecule) are type I transmembrane proteins that bind distinct members of the class III secreted semaphorin subfamily that are implicated in repulsive axon guidance. Neuropilin extracellular domains contain two CUB (complement-binding) domains, two domains with homology to coagulation factors V and VIII, and a MAM (meprin) domain. In the absence of ligands, neuropilins can form homo- and hetero-oligomers via their MAM domains. Expression in developing neurons of the central and peripheral nervous systems is somewhat overlapping but distinct. Npn-1 and Npn-2 are also receptors for VEGF165 on endothelial and tumor cells.
- Shipping Conditions:
- Ambient